Maladies auto-immunes neurologiques

2018
Autologous haematopoietic stem cell transplantation for neurological diseases.
Burman J, Tolf A, Hägglund H, Askmark H.
J Neurol Neurosurg Psychiatry. 2018 Feb;89(2):147-155

2017
Autologous hematopoietic stem cell transplantation for pediatric multiple sclerosis: a registry-based study of the Autoimmune Diseases Working Party (ADWP) and Pediatric Diseases Working Party (PDWP) of the European Society for Blood and Marrow Transplantation (EBMT).
Burman J, Kirgizov K, Carlson K, Badoglio M, Mancardi GL, De Luca G, Casanova B, Ouyang J, Bembeeva R, Haas J, Bader P, Snowden J, Farge D.
Bone Marrow Transplant. 2017 Aug;52(8):1133-1137

Autologous haematopoietic stem cell transplantation for treatment of multiple sclerosis.
Muraro PA, Martin R, Mancardi GL, Nicholas R, Sormani MP, Saccardi R.
Nat Rev Neurol. 2017 Jun 16. doi: 10.1038/nrneurol.2017.81

Myasthenia gravis after allogeneic bone marrow transplantation: A case report and literature review.
Tsutsumi Y, Kamiishi T, Kikuchi R, Ito S, Matsuoka S, Teshima T.
Hematol Oncol Stem Cell Ther. 2017 May 18. pii: S1658-3876(17)30052-3. doi: 10.1016/j.hemonc.2017.04.001.

Selection of Patients With Multiple Sclerosis to Undergo Autologous Hematopoietic Stem Cell Transplantation.
Racke MK, Imitola J.
JAMA Neurol. 2017 Apr 1;74(4):392-394. doi: 10.1001/jamaneurol.2016.5925.

NEDA status in highly active MS can be more easily obtained with autologous hematopoietic stem cell transplantation than other drugs.
Sormani MP, Muraro PA, Saccardi R, Mancardi G.
Mult Scler. 2017 Feb;23(2):201-204. doi: 10.1177/1352458516645670.

Long-term Outcomes After Autologous Hematopoietic Stem Cell Transplantation for Multiple Sclerosis.
Paolo A. Muraro, MD; Marcelo Pasquini, MD; Harold L. Atkins, MD; James D. Bowen, MD; Dominique Farge, MD; Athanasios Fassas, MD; Mark S. Freedman, MD; George E. Georges, MD; Francesca Gualandi, MD; Nelson Hamerschlak, MD; Eva Havrdova, MD; Vassilios K. Kimiskidis, MD; Tomas Kozak, MD; Giovanni L. Mancardi, MD; Luca Massacesi, MD; Daniela A. Moraes, MD; Richard A. Nash, MD; Steven Pavletic, MD; Jian Ouyang, MD; Montserrat Rovira, MD; Albert Saiz, MD; Belinda Simoes, MD; Marek Trneny, MD; Lin Zhu, MD; Manuela Badoglio, MSc; Xiaobo Zhong, MS; Maria Pia Sormani, PhD; Riccardo Saccardi, MD; for the Multiple Sclerosis–Autologous Hematopoietic Stem Cell Transplantation (MS-AHSCT) Long-term Outcomes Study Group
JAMA Neurol. Published online February 20, 2017. doi:10.1001/jamaneurol.2016.5867

Autologous hematopoietic cell transplantation in multiple sclerosis.
Bell SM, Sharrack B, Snowden JA.
Expert Opin Biol Ther. 2017 Jan;17(1):77-86.

2016
Immunoablation and autologous haemopoietic stem-cell transplantation for aggressive multiple sclerosis: a multicentre single-group phase 2 trial.
Atkins HL, Bowman M, Allan D, Anstee G, Arnold DL, Bar-Or A, Bence-Bruckler I, Birch P, Bredeson C, Chen J, Fergusson D, Halpenny M, Hamelin L, Huebsch L, Hutton B, Laneuville P, Lapierre Y, Lee H, Martin L, McDiarmid S, O’Connor P, Ramsay T, Sabloff M, Walker L, Freedman MS.
Lancet. 2016 Aug 6;388(10044):576-85. doi: 10.1016/S0140-6736(16)30169-6.

Distinct oligoclonal band antibodies in multiple sclerosis recognize ubiquitous self-proteins.
Brändle SM, Obermeier B, Senel M, Bruder J, Mentele R, Khademi M, Olsson T, Tumani H, Kristoferitsch W, Lottspeich F, Wekerle H, Hohlfeld R, Dornmair K.
Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7864-9. doi: 10.1073/pnas.1522730113.

Antibodies in multiple sclerosis oligoclonal bands target debris.
Winger RC, Zamvil SS.
Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7696-8. doi: 10.1073/pnas.1609246113.

Myasthenia Gravis Treated With Autologous Hematopoietic Stem Cell Transplantation.
Bryant A, Atkins H, Pringle CE, Allan D, Anstee G, Bence-Bruckler I, Hamelin L, Hodgins M, Hopkins H, Huebsch L, McDiarmid S, Sabloff M, Sheppard D, Tay J, Bredeson C.
JAMA Neurol. 2016 Jun 1;73(6):652-8. doi: 10.1001/jamaneurol.2016.0113

2015
Autologous hematopoietic stem cell transplantation in multiple sclerosis: a phase II trial.
Mancardi GL, Sormani MP, Gualandi F, Saiz A, Carreras E, Merelli E, Donelli A, Lugaresi A, Di Bartolomeo P, Rottoli MR, Rambaldi A, Amato MP, Massacesi L, Di Gioia M, Vuolo L, Currò D, Roccatagliata L, Filippi M, Aguglia U, Iacopino P, Farge D, Saccardi R; ASTIMS Haemato-Neurological Collaborative Group, On behalf of the Autoimmune Disease Working Party (ADWP) of the European Group for Blood and Marrow Transplantation (EBMT); ASTIMS Haemato-Neurological Collaborative Group On behalf of the Autoimmune Disease Working Party ADWP of the European Group for Blood and Marrow Transplantation EBMT.
Neurology. 2015 Mar 10;84(10):981-8. doi: 10.1212/WNL.0000000000001329.

Autologous hematopoietic stem cell transplantation in neuromyelitis optica: a registry study of the EBMT Autoimmune Diseases Working Party.
Greco R, Bondanza A, Oliveira MC, Badoglio M, Burman J, Piehl F, Hagglund H, Krasulova E, Simões BP, Carlson K, Pohlreich D, Labopin M, Saccardi R, Comi G, Mancardi GL, Bacigalupo A, Ciceri F, Farge D.
Mult Scler. 2015 Feb;21(2):189-97. doi: 10.1177/1352458514541978.

2012
A prospective, randomized, controlled trial of autologous haematopoietic stem cell transplantation for aggressive multiple sclerosis: a position paper.
Saccardi R, Freedman MS, Sormani MP, Atkins H, Farge D, Griffith LM, Kraft G, Mancardi GL, Nash R, Pasquini M, Martin R, Muraro PA; European Blood and Marrow Transplantation Group; Center for International Blood and Marrow Research; HSCT in MS International Study Group.
Mult Scler. 2012 Jun;18(6):825-34. doi: 10.1177/1352458512438454.

Autologous hematopoietic stem cell transplantation for multiple sclerosis–if confused or hesitant, remember: ‘treat with standard immune suppressive drugs and if no inflammation, no response.
Burt RK, Balabanov R, Voltarelli J, Barreira A, Burman J.
Mult Scler. 2012 Jun;18(6):772-5. doi: 10.1177/1352458512442993.

2010
Hematopoietic stem cell transplantation for multiple sclerosis: collaboration of the CIBMTR and EBMT to facilitate international clinical studies.
Pasquini MC, Griffith LM, Arnold DL, Atkins HL, Bowen JD, Chen JT, Freedman MS, Kraft GH, Mancardi GL, Martin R, Muraro PA, Nash RA, Racke MK, Storek J, Saccardi R.
Biol Blood Marrow Transplant. 2010 Aug;16(8):1076-83. doi: 10.1016/j.bbmt.2010.03.012.

New onset of myasthenia gravis after treatment of systemic sclerosis by autologous hematopoietic stem cell transplantation: sustained autoimmunity or inadequate reset of tolerance?
Deligny C, Clave E, Sibon D, Daikeler T, Keshmandt H, Carmagnat M, Douay C, Arfi S, Clair B, Toubert A, Farge D.
Hum Immunol. 2010 Apr;71(4):363-5. doi: 10.1016/j.humimm.2010.01.013.

Autologous hematopoietic stem cell transplantation for autoimmune diseases: an observational study on 12 years’ experience from the European Group for Blood and Marrow Transplantation Working Party on Autoimmune Diseases.
Farge D, Labopin M, Tyndall A, Fassas A, Mancardi GL, Van Laar J, Ouyang J, Kozak T, Moore J, Kötter I, Chesnel V, Marmont A, Gratwohl A, Saccardi R.
Haematologica, 2010 Feb;95(2):284-92. doi: 10.3324/haematol.2009.013458.

2008
Autologous haematopoietic stem-cell transplantation in multiple sclerosis.
Mancardi G, Saccardi R.
Lancet Neurol. 2008 Jul;7(7):626-36. doi: 10.1016/S1474-4422(08)70138-8.

Immunoablation and autologous hematopoietic stem cell transplantation (AHSCT) in multiple sclerosis.
Créange A, Farge-Bancel D.
Rev Neurol (Paris). 2008 Mar;164(3):207-15. doi: 10.1016/j.neurol.2007.10.001.

2004
Consensus statement concerning cardiotoxicity occurring during haematopoietic stem cell transplantation in the treatment of autoimmune diseases, with special reference to systemic sclerosis and multiple sclerosis.
Saccardi R, Tyndall A, Coghlan P, Denton C, Edan G, Emdin M, Farge D et al.
Bone Marrow Transplant. 2004 Nov;34(10):877-81.